1. Los Angeles City and
California State, USA
Epidemic among personnel at L.A. County Hospital, Ruth Protection
Home and throughout California, paralleling poliomyelitis, often
diagnosed as atypical poliomyelitis, sometimes including
An outbreak of "encephalitis" in St. Agnes Convent.
3. Erstfeld, Switzerland
Outbreak described as "Abortive Poliomyelitis."
St. Gallen, Switzerland
Outbreak in Frohburg Hospital described as "Abortive
5. Middlesex, England
Outbreak at Harefield Sanatorium - "Persitent myalgia
following sore throat."
Degersheim, St. Gallen, Switzerland
Outbreak described as "Abortive Poliomyelitis."
University Hospital of Pennsylvania, USA
Epidemic described as "pleurodynia with
prominent neurological symptoms and no demonstrable cause."
"Mixed epidemics of poliomyelitis and a disease resembling
poliomyelitis with the character of the Akureyri Disease."
9. North Coast Towns, Iceland
"A disease epidemic in Iceland simulating Poliomyelitis" in three
separate towns during this time.
10. Adelaide, South Australia
Outbreak of a disease resembling poliomyelitis.
11. Louisville, Kentucky, USA
Outbreak in the Nurse's Training School of St. Joseph Infirmary,
later described as "epidemic neuromyasthenia."
Upper New York State
Outbreak described as resembling the "Iceland Disease...simulating
Acute Anterior Poliomyelitis."
13. London, England
Outbreak at Middlesex Hospital Nurses' Home described as
"Encephalomyelitis associated with Poliomyelitis Virus."
Outbreak described as "epidemic myositis."
Lakeland, Florida, USA
Outbreak described as epidemic neuromyasthenia.
16. Coventry and Coventry
"An illness resembling Poliomyelitis observed in nurses."
Rockville, Maryland, USA
Chestnut Lodge Hospital student nurses described with
poliomyelitis-like epidemic neuromyasthenia.
Outbreak of "Epidemic encephalitis with vertigo."
19. Tallahassee, Florida, USA
Bond JO. A new clinical entity? Lancet 1956; 2:256.
Outbreak described as "Benign Myalgic Encephalomyelitis (Iceland
Among the British Army, a "further outbreak of a disease
Outbreak among medical and nursing staff in a Liverpool Hospital.
23. Dalston, Cumbria, England
"...an unusual disease seen in epidemic and sporadic form in
general practice in 1955 and subsequent years."
Famous outbreak of benign myalgic encephalomyelitis among Royal
Free Hospital staff.
Perth, Western Australia
"Virus epidemic in recurrent waves."
Gilfach Goch, Wales
Outbreak of Benign encephalomyelitis.
Durban and Durban City, South Africa
Outbreak among nurses at Addington Hospital called "The Durban
Mystery Disease" describing neuromuscular dysfunction, and
epidemic myalgic encephalomyelopathy, including sporadic cases in
Johannesburg of a outbreak resembling poliomyelitis.
28. Segbwema, Sierra
An outbreak of encephalomyelitis.
Patreksfordur and Thorshofn, Iceland
Unusual response to poliomyelitis vaccination.
North West London, England
Outbreak of acute infective encephalomyelitis simulating
poliomyelitis among a residential home for nurses.
An epidemic of neuromyasthenia.
Punta Gorda, Florida, USA
An outbreak of epidemic neuromyasthenia.
Newton-le-Willows, Lancashire, England
Outbreak described as "lymphocytic meningo-encephalitis with
myalgia and rash," "An outbreak of a disease believed to have been
cause by Echo 9 virus," with other varying descriptions.
Pittsfield, Williamstown, Massachusetts, USA
Outbreak of "epidemic neuromyasthenia" later described as benign
myalgic encephalomyelitis. (Included in this summary are
sporadic cases in Hygiea, Sweden, with descriptions of
encephalitis, meningitis or poliomyelitis; Coxsackie B and Echo
Virus infections; benign myalgic encephalomyelitis.)
35. Coventry, England
Outbreak described as epidemic malaise and benign myalgic
36. Brighton, South Australia
Outbreak described as "Coxsackie, Echo Virus meningitis and
mylagic encephalomyelitis", "Epidemic myalgic encephalomyelitis,"
and "Benign myalgic encephalomyelitis."
37. Athens, Greece
An outbreak of benign myalgic encephalomyelitis in a nurse's
school, "periostitis and arthropathy noted." (Included in
this summary is an outbreak of benign myalgic encephalomyelitis in
S.W. London, England
Reports of sporadic cases of myalgic encephalomyelitis.
38. Newcastle upon Tyne,
Outbreak of benign myalgic encephalomylitis.
N.W. London, England
Reports of sporadic cases of influenza-like illness
Article describing sporadic cases and "The psychiatric sequelae of
Benign Myalgic Encephalomyelitis."
Sporadic case of benign myalgic encephalomyelitis described.
39. New York State, USA
Outbreak described as epidemic neuromyasthenia in a convent in New
40. N.W. London, England
Outbreak described as epidemic malaise and epidemic
Franklin, Kentucky, USA
Outbreak of "neurmyasthenia" in a Kentucky factory, possibly due
to mercury exposure.
42. Galveston County, Texas,
Outbreak described as "Epidemic Neuromyasthenia Variant?" and
"Epidemic Diencephalomyelitis," the latter describing
neuropsychiatric, cardiovascular and endocrine disorders.
Sporadic cases resembling benign myalgic encephalomyelitis.
43. Fraidek, Lebanon
Report on an epidemic of benign myalgic encephalomyelitis.
44. State University of New
Medical Centre - report of epidemic Neuromyasthenia and
"unidentified symptom complex."
45. Lackland Air Force Base,
Epidemic Neuromyasthenia reported. "A syndrome or disease?"
46. London, England
An outbreak of "epidemic neuromyasthenia" among nurses a the
Hospital for Sick Children, Great Oromond Street.
47. Sacramento, California, USA
"200 hospital staff in the [Mercy San Juan Hospital] fell ill in
August September 1975. The epidemic appears to have spread
to the children of the hospital staff and from there to the
children's teachers. 43 have been seriously disabled with
chronic illness from 1975-1992" [at publication of this text].
48. Southwest Ireland
Reports on Mylagic Encephalomyelits and epidemic neuromyasthenia
in this region.
49. Dallas-Fort Worth, Texas,
"Epidemic Neuromyasthenia" reported.
[Ed. note: Dr. Hyde's text notes that the first major M.E./CFS
Symposium was held at the Royal Society of Medicine in London in
this year. M.E. aka epidemic neuromyasthenia, viral
relationships to this disease, biochemical abnormalities in
patients and other subjects were discussed by experts such as
Shelokov, Ramsay, Richardson, Behan, Parish and others.]
50. Southampton, England
Outbreak of M.E. in a girls' school.
51. West Kilbridge, Ayrshire,
M.E. epidemic reported in a rural medical practice.
52. Helensburgh, Scotland
Coxsackie B outbreak reported in a general practice.
Sporadic cases of M.E. reported.
53. West Otago, New Zealand
Outbreak first described and an "unexplained illness," later as
M.E. Included here are outbreaks in Dunedin and Hamilton
"From 1984 until 1992 [at publication of this text] an endemic
period occurred in which an usually large number of cluster and
epidemics of M.E./CFS have been recognized in North America.
After an apparent initial increase in the morbidity in 1983 there
seemed to have appeared in late summer of 1984 an unprecedented
increase of sporadic and epidemic cases across North America.
Although certain geographical hot spots seen to have taken up much
of the medical interest, this endemic situation probably
represents an unusual and unremitting morbidity in all areas of
the United States and Canada." -Dr. Byron Hyde-
Incline Village, Lake Tahoe, Nevada, USA
"A chronic illness characterized by fatigue, neurlogic and
immunologic disorders and active human herpesvirus type 6
infection." "This community epidemic, apparently started in
a girls' basketball team, then involved primarily teacher in at
lest three high schools, and then large numbers of the community."
Chapel Hill, North Carolina, USA
"Epidemic amongst members of The North Carolina Symphony
Orchestra. Low NKC [Natural Killer Cells] associated with
high yield of lymphoma, astrocytoma, glioma."
Montreal, Quebec-Ontario, Canada
"Over 500 cases of M.E./CFS documented during August-November 1984
period. This endemic was active in all parts of Canada
during this period and appears [to] have maintained its activity
until the time of writing in 1991."
57. Truckee, California, USA
M.E. epidemic involving teachers and students.
58. Lyndonville, New York,
M.E. epidemic in a rural community involving children and adults.
Yerington, Nevada, USA
"In the same area [not far from Truckee, California] an M.E./CFS-like epidemic reputedly occurred in
a reservation of American Native people."
60. Placerville, California,
"Outbreak of chronic fatigue syndrome 'coincident with a heavy
contamination of the local unfiltered water supply'."
61. Sonora, California, USA
"More than 35 children and adults were diagnosed with M.E. in the
mountain country 100 miles from Lake Tahoe. Many of these
patients were associated in some way with Columbia Community
62. Roseville, California,
Rosedale Hopital reported 11 cases of M.E./CFS among staff.
63. Elk Grove, California,
M.E. epidemic among teachers and students.